Research Spotlight: Slippery surfaces that speed up life-saving diagnostics

College of Engineering
Microfluidic devices can reveal infections, track treatment response, and guide personalized therapies. They power many of today’s vital medical tests, but if the fluid hesitates or sticks to the surface, results can be skewed, take longer, and cost more to produce.

Drops of liquid on dish

Bei Fan, assistant professor in the Department of Mechanical Engineering at Michigan State University, and her team have developed a new slippery coating that helps liquids travel smoothly. This thin, liquid-like layer is made up of small mobile molecules. The layer feels slick at the molecular level, so fluid samples glide across it instead of clinging to or blocking the channel.

Professional Headshot of Bei Fan

In testing, fluids move with noticeably lower resistance and avoid typical buildup. The coating stayed clear and stable even after repeated use, which is essential for optical sensors and point-of-care devices.

Single-droplet medical tests thrive on low friction. Faster fluid motion supports rapid, low-cost diagnostics. Smoother channels also reduce the amount of sample and reagent required, creating less waste and lowering the environmental footprint of disposable tests. In wearable and implantable systems, reduced drag can lead to smaller pumps and longer device lifetimes.

Fan’s work strengthens the foundation for more accessible diagnostics, better monitoring tools, and cleaner lab processes that reach more people at lower cost.

To explore Fan’s research further, visit:

 

This research was sourced from the College of Engineering.

 

Opportunities for Partnership

The MSU Innovation Center is seeking companies and organizations interested in microfluidic technologies, point-of-care diagnostics, and surface engineering solutions.

Whether you’re exploring sponsored research, licensing opportunities, or co-developing liquid-like surface coatings, lab-on-a-chip devices, or sustainable diagnostic testing innovations, we’re ready to collaborate.

Interested in partnering with MSU faculty on microfluidics research and next-generation diagnostic device technologies?

Visit innovationcenter.msu.edu or contact us to start the conversation.

About the MSU Innovation Center
The MSU Innovation Center is Michigan State University’s hub for corporate partnerships, technology commercialization, and startup support. By integrating MSU Technologies, Business Connect, and Spartan Innovations, the Center transforms groundbreaking research into real-world impact. Each year, the Innovation Center helps launch more than 130 discoveries into patented products and startup ventures, advancing economic development and improving lives locally and globally. Through strategic collaborations with faculty, industry, and investors, the Center accelerates innovation from concept to market—empowering Spartans to lead in entrepreneurship, research translation, and public-private partnerships. Learn more at innovationcenter.msu.edu

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